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BRL 52537 hydrochloride
CAS No. 112282-24-3
BRL 52537 hydrochloride ( —— )
产品货号. M27458 CAS No. 112282-24-3
BRL 52537 盐酸盐是一种选择性和特异性 KOR 激动剂，与缺血性神经元损伤的神经保护作用有关。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥956 | 有现货 |
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| 5MG | ￥1401 | 有现货 |
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| 10MG | ￥2001 | 有现货 |
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| 25MG | ￥3718 | 有现货 |
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| 50MG | ￥5451 | 有现货 |
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| 100MG | ￥7760 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BRL 52537 hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述BRL 52537 盐酸盐是一种选择性和特异性 KOR 激动剂，与缺血性神经元损伤的神经保护作用有关。
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产品描述BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury. It is used for research into potential treatments for stroke and heart attack as well as more general brain research.(In Vivo):In rats treated with BRL 52537 during ischemia and early reperfusion, infarct volume was significantly attenuated in cortex and in caudoputamen.
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体外实验——
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体内实验——
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同义词——
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通路Endocrinology/Hormones
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靶点Opioid Receptor
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受体RARγ
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研究领域——
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适应症——
化学信息
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CAS Number112282-24-3
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分子量391.76
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分子式C18H25Cl3N2O
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(Cc(cc1)cc(Cl)c1Cl)N1C(CN2CCCC2)CCCC1.Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Hughes NE, et al. Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3274-3277.
